Penicillium chrysogenum

By: - Updated: August 26, 2018

Previously known as Penicilliumnotatum, Penicillium chrysogenum is a widely studied species of Penicillium that is most famous for being a source of penicillin and antibiotics. P. chrysogenum can most often be found in indoor environments, particularly in those with high humidity, dampness, or previous water damage.

In appearance, P. chrysogenum is blue-green in colour with a yellow pigment at times. However, identifying P. chrysogenum based on colour alone is not possible.

P. chrysogenum is well-known as both an allergen and pathogen, although it has rarely been reported as a cause of human disease. Symptoms include pulmonary infection, pneumonia, localized granulomas, fungus balls, and systemic infection. However, it is difficult to make a proper diagnosis given that these symptoms are so common.

What is Penicillium chrysogenum?

Penicillin is one of the oldest broad spectrum antibiotics which are used to treat various types of infections. Though today more effective sources of antibiotics have been invented, there still continues to be regular use of various derivatives of penicillium.

One such fungus is known by the name penicillium chrysogenum. It is a widely researched type of penicillium and even today it continues to be used for treatment various infections and diseases. We will do a reasonably comprehensive review of penicillium chrysogenum for the benefit of our readers and those who would like to do further research on the subject.

It also could be useful for patients who are looking at penicillin as a source of antibiotic for treating different types of infections caused by bacteria.

What are sources Of Penicillium chrysogenum?

Penicillium has got its name because it is derived from structures which are capable of producing spores. These structures are also referred to as conidiophores. They actually belong to a fungus and are found in various places including soil, air, vegetables that are decaying, air amongst other things. It is now possible to extensively cultivate and grow this antibiotic source of fungus under carefully simulated conditions.

Some important facts about Penicillium chrysogenum

Apart from being used as a raw material for making effective antibiotics, there are a number of interesting facts about penicillium chrysogenum. It would be interesting to have a look at a few of the facts surrounding this fungus.

Penicillium grows best when it has the right aid supporting its growth. Yeast is extensively used for growing this fungus in controlled environments. It therefore is used for making organic acids and cheese and of course for large scale manufacture of antibiotics. It can be divided into two major segments, natural and semi-synthetic. While the former is made during the fermentation of the mold, the latter is made artificially. This is done by modifying six aminopenicillianic acids.

The only completely natural form of penicillium chrysogenum is penicillin G. However, its therapeutic use is limited because of very poor acid-stability.

What are Penicillium chrysogenum growth conditions?

The best thing about penicillium is that it grows well in a number of conditions. In fact it is quite possible that it could be growing right now in your home and surroundings.

It grows well in indoor environments, and water damaged or damp buildings are often considered to be excellent source for the growth of this fungus. It can also be grown well on yeast, cheese and other such milk products which have a tendency to decompose and decay after a period of time.

It can also grow on food items which are stale and left open and uncovered. The penicillium fungus is also found aplenty in soil.

What diseases does Penicillium Chrysogenum cause?

Though penicillium is a safe fungus in its natural form with very little reports of side effects and dangers, it could be the cause of a few diseases which all the stakeholders must be aware of. There have been some instances of nervousness and palpitation which have been attributed to use of penicillium chrysogenum.

In a few cases, instances of Nervous System Infectious Disorders have been reported. However, such instances are few and far between and they are considered more as an exception than a general rule. Lung related problems could also be caused by penicillium chrysogenum.

What Allergies are related o Penicillium chrysogenum?

Like all funguses, it is quite obvious that there could be some allergic manifestation caused by penicillium chrysogenum. However, on the whole the allergic reactions are very few and therefore on the whole it is considered safe. But those who are allergic to molds and mites should be careful when using penicillium derivatives.

They could suffer from breathing related problems, skin allergies, constant sneezing and red/watery eyes amongst others. Hence those with breathing and bronchial problems would do well to be aware of the allergy related risks before using penicillium chrysogenum.

What about Penicillium Chrysogenum Mold?

While the final product of penicillium fungus could be very useful in treating a number of bacterial infections, we need to know something more about it in the mold form.

In its natural form it is known to cause food spoilage. It also is known to colonize leather products. Therefore if shoes, jackets, belts, leather sofa and other such products are kept in a damp and uninhabited surrounding for long period of time, it could be lead to penicillium mold build up.

A few species of molds could also trigger toxic compounds also known as mycotoxins. Those who are allergic to certain molds could also suffer from side effects. However, it is not the case with all types of penicillium molds. There are around 200 types of molds and not all of them are allergic.

How to get rid of Penicillium chrysogenum mold?

If you come across the growth of penicillium chrysogenum mold, it is important that you take steps to get rid of the same as soon as possible. This is because it could lead a number of allergic manifestations, a few of which could be bothersome and even dangerous.

The first task is to spray water in the growth. This will reduce the number of spores which are released into the air when the cleaning process is undertaken. A damp cloth should be used to clean the walls and other surfaces where there is a growth of this fungal mold. You should also then finally clean the entire area with a combination of one gallon of warm water mixed with half a cup of household bleach. This should kill the fungus quite thoroughly.

But, the best advice for proper Penicillium chrysogenum mold removal, is to contact professional mold remediation company like Mold Busters.

For professional mold testing of P. chrysogenum and other types of mold, contact Mold Busters. We offer comprehensive mold testing services that include surface sampling (tape/swab/bulk) and air sampling (viable/non-viable).